Package: GxEprs
Title: Genotype-by-Environment Interaction in Polygenic Score Models
Version: 1.3
Authors@R: c(person("Dovini", "Jayasinghe", role = c("aut", "cre","cph"), email = "dovini.jayasinghe@mymail.unisa.edu.au"),
             person("Hong", "Lee", role = c("aut","cph"),email = "Hong.Lee@unisa.edu.au"),
             person("Moksedul", "Momin", role = c("aut","cph"), email = "md_moksedul.momin@mymail.unisa.edu.au"))
Description: A novel PRS model is introduced to enhance the prediction
        accuracy by utilising GxE effects. This package performs Genome
        Wide Association Studies (GWAS) and Genome Wide Environment
        Interaction Studies (GWEIS) using a discovery dataset. The
        package has the ability to obtain polygenic risk scores (PRSs)
        for a target sample. Finally it predicts the risk values of
        each individual in the target sample. Users have the choice of
        using existing models (Li et al., 2015)
        <doi:10.1093/annonc/mdu565>, (Pandis et al., 2013)
        <doi:10.1093/ejo/cjt054>, (Peyrot et al., 2018)
        <doi:10.1016/j.biopsych.2017.09.009> and (Song et al., 2022)
        <doi:10.1038/s41467-022-32407-9>, as well as newly proposed
        models for genomic risk prediction (refer to the URL for more
        details).
URL: https://github.com/DoviniJ/GxEprs
License: GPL (>= 3)
Encoding: UTF-8
Depends: R (>= 3.5)
LazyData: true
NeedsCompilation: no
Packaged: 2026-10-17 08:14:02 UTC; root
Author: Dovini Jayasinghe [aut, cre, cph], Hong Lee [aut, cph],
        Moksedul Momin [aut, cph]
Maintainer: Dovini Jayasinghe <dovini.jayasinghe@mymail.unisa.edu.au>
Config/roxygen2/version: 8.0.0
Repository: https://dovinij.r-universe.dev
Date/Publication: 2026-05-29 08:37:04 UTC
RemoteUrl: https://github.com/dovinij/gxeprs
RemoteRef: HEAD
RemoteSha: d9c5016e3603952c85d0ee4b6bbb62b940903b4a